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Tuesday, August 11, 2020 | History

2 edition of Brokaw Mechanism and Control of Ciliary Movement found in the catalog.

Brokaw Mechanism and Control of Ciliary Movement

CJ BROKAW

Brokaw Mechanism and Control of Ciliary Movement

by CJ BROKAW

  • 319 Want to read
  • 21 Currently reading

Published by John Wiley & Sons Inc .
Written in English

    Subjects:
  • Clinical & Internal Medicine

  • The Physical Object
    FormatHardcover
    Number of Pages256
    ID Numbers
    Open LibraryOL10330323M
    ISBN 100471563676
    ISBN 109780471563679

    In this chapter, the structure of the mucociliary interface, the mechanics and coordination of ciliary activity, and the intra-and intercellular mechanisms that regulate airway ciliary activity will be briefly reviewed. Limited space necessitates that reference to many original studies is directed through reviews and recent reports []. Rather, this regulatory mechanism appears to be required for controlling the form of forward and reverse bends important for normal flagellar movement. Consistent with this interpretation, mutations that lead to a failure in I1 dynein assembly are defective in flagellar waveform (Brokaw and Kamiya, ) and fail to undergo normal phototaxis.

    Developmental changes in the pattern of ciliary response and the swimming behavior in some invertebrate larvae. In Swimming and Flying in Nature, vol. BROKAW, C. J. (). Microtubule sliding in swimming sperm flagella: direct and indirect measurements on sea urchin and tunicate spermatozoa. Ce//Bio/. , BROKAW, C. J. (). Satir P. Studies on cilia. 3. Further studies on the cilium tip and a "sliding filament" model of ciliary motility. J Cell Biol. Oct; 39 (1)– [PMC free article] Summers KE, Gibbons IR. Adenosine triphosphate-induced sliding of tubules in trypsin-treated flagella of sea-urchin sperm. Proc Natl Acad Sci U S A. Dec; 68 (12)

    Brokaw's () curvature control model presents a simplified view of the transmission, which remains to be completely specified. In normal ciliary motility, the control of such transmission is very complex, which permits a wide variety of bending waves of different magnitudes and timing to . Primary ciliary dyskinesia: mechanisms and management Nadirah Damseh,1 Nada Quercia,1,2 Nisreen Rumman,3 Sharon D Dell,4 Raymond H Kim5 1Division of Clinical and Metabolic Genetics, 2Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada; 3Pediatric Department, Makassed Hospital, Jerusalem, Palestine; 4Division of Respiratory Medicine, Department of Pediatrics, Child.


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Brokaw Mechanism and Control of Ciliary Movement by CJ BROKAW Download PDF EPUB FB2

Mechanism and control of ciliary movement: international meeting held at Friday Harbor, Washington, SeptemberAuthor: Charles J Brokaw ; Pedro Verdugo. The mechanism of ciliary movement. III. It is well known that Paramecium (1) is cathodally galvanotactic in mixtures of sodium and calcium salts because of ciliary reversal at the cathodal end, and that (2) the cilia also may be reversed in solutions rich in monovalent cations or in barium or manganese ions, Cited by: 4.

Brokaw, C. and I. Gibbons () Mechanisms of movement in flagella and cilia. In: Swimming and Flying in Nature, T. Y.-T. Wu, C. Brokaw and C. Brennan, eds., Plenum Pub.

Corp. N.Y., pp. Brokaw, C. and D. Rintala () Computer simulation of flagellar movement. Key words: cilium, model, movement mechanism, infusorian, movement control, identification 1.

Introduction An investigation into the mechanism of ciliary movement is one of the interesting and actual prob-lems of modern microbiology and medicine. The cil-ium is a microtubule-based motile organelle of some.

Charles J. Brokaw's research works with 6, citations and 2, reads, including: Computer Simulation of Flagellar Movement X. Doublet pair splitting and bend propagation modeled using.

The Mechanism of Ciliary Movement. in sea-water the gill is in an environment which may have a sub-normal concentration of potassium. In contrast to the lateral cilia, the fron to-lateral, the frontal and the terminal cilia beat normally for very long periods (more. Mechanics of ciliary transport.

In C. Brokaw & P. Verdugo (eds), Mechanism and control of ciliary movement. Cell Motility (Supplement 1), Alan R. Liss, Inc., N.Y.: 41– This study focuses on the mechanics of ciliary movement of ctenophores in relation to locomotion and feeding, with field and laboratory observations documented with 35 mm photographs and video sequences.

Movement through the water is strongly modified by subtleties of body morphology. Whereas the entire ctenophore moves in a flow regime where the Reynolds numbers range from to. Interaction between dynein and tubulin underlies the basic mechanism of ciliary and flagellar movement. The cilia and flagella demembranated with Triton X can be reactivated by adding ATP, showing similar movement to that of intact ones.

When the fragments of demembranated cilia and flagella are digested with trypsin to take off the hoops. Cilia and Ciliary Movements. A second type of cellular motion, ciliary movement, is a whiplike movement of cilia on the surfaces of cells.

This occurs in only two places in the human body: on the sufaces of the respiratory airways and on the inside surfaces of the uterine tubes (fallopian tubes) of the reproductive tract.

In the nasal cavity and lower respi-ratory airways, the whiplike motion. Ions and Ciliary Activity 8.

Oxygen, Respiration and Ciliary Activity 9. Adenosine Triphosphate and Ciliary Activity Hormones and Ciliary Activity Effects of Other Chemicals on Ciliary Activity Control of Ciliary Activity by the Organism Microdissection Studies on Ciliated Tissues 4 The Movement Of Cilia And Flagella 1.

Ciliary movement is driven by systematic regulation of both the outer dynein arm (ODA) and the inner dynein arm (IDA) activities. Detailed characterization of the subunit composition and assembly of the dynein motors into the axoneme is detailed in Chapter 5 (vol.

1 of this book). Author(s): Brokaw,Charles J; Verdugo,Pedro; International Meeting on the Mechanism and Control of Ciliary Movement,( Friday Harbor, Wash.) Title(s): Mechanism and control of ciliary movement: international meeting held at Friday Harbor, Washington, September/ editors, Charles J.

Brokaw, Pedro Verdugo, with the assistance of Ian R. Gibbons. Eshel D, Brokaw CJ () New evidence for a “Biased Baseline” mechanism for calcium-regulated asymmetry of flagellar bending. Cell Motil Cytoskel 7: – CrossRef Google Scholar Gibbons BH, Gibbons IR () Flagellar movement and adenosine triphosphatase ac¬tivity in sea urchin sperm extracted with Triton X mechanism underlying ciliary bending.

This chapter primarily focuses on the regulatory structures, mechanisms, and signaling molecules, revealed in studies using Chlamydomonas and other experimental systems, that control axonemal bending. 1. Introduction. Understanding the mechanism of ciliary / flagellar movement is crucial: motile cilia play essential roles in human development, male and female fertility, protection and function of the airway and circulation of cerebral spinal fluid [1, 2].Defects in ciliary motility lead to a variety of “ciliopathies” that can result in an especially wide range of diseases and syndromes.

For Paramecimn, when care is taken to prevent decil- iation, the demembranated cells swim when reacti- vated and swimming speed increases as a function of cAMP concentration from IJM. These findings TRENDS IN CELL BIOLOGY VOL.

3 NOVEMBER The control of ciliary beat frequency Ciliary movement is powered by axonemal dynein. () in Mechanism and Control of Ciliary Movement (Brokaw, C.

J., and, P., Eds.), pp.A. Liss, New York. Eckert, R., Naitoh, Y., and Machemer, H. () Symp. Soc. Exp. new insight into the nature of the beating mechanism. Competing views on how switching is controlled Curvature control The first mechanistic proposal for the control of switching was the ‘curvature control’ hypothesis of Brokaw (Brokaw, ; Brokaw, a; Brokaw, b).

Curvature is a mechanical parameter of the axoneme. Brokaw CJ () Movement and nucleoside polyphosphatase activity of Bonini MN, Nelson DL () Membrane potential regulation of cAMP: control mechanism for the swimming behaviour in Paramecium.

Soc () Reactivated Triton-extracted models of Paramecium modification of ciliary movement by calcium ions. Science –. The working mechanism of the eukaryotic flagellar axoneme remains one of nature's most enduring puzzles.

The basic mechanical operation of the axoneme is now a story that is fairly complete; however, the mechanism for coordinating the action of the dynein motor proteins to produce beating is still controversial.

Although a full grasp of the dynein switching mechanism remains elusive, recent. The motility of demembranated fowl spermatozoa was vigorous at 30°C, but decreased markedly following the addition of mitogen-activated protein (MAP) .Activation of the Ciliary Mechanism.

That the ciliary mechanism is not controlled by a nervous system has been supported by work done by Lucas and Douglas, 1 and by Kordik, Burn, and Bulbring. 2 The former team, using an in situ preparation of turtle trachea were unable to demonstrate a change in rate of ciliary beat after intravenous injection.